Automated Optical Microscopy

ImageXpress Micro Confocal

ImageXpress Micro Confocal

ImageXpress Micro Confocal Imager

Features include: 

  • Automated imaging of fixed or live cells in multi-well plates or glass slides

  • Widefield imaging or spinning disk confocal imaging with 42µm and 60µm pinholes

  • Solid-state light engine and filter sets for DAPI, FITC, TRITC, TxRed and Cy5 fluorescence

  • High quantum efficiency 16-bit sCMOS camera enabling >3 log dynamic range and a large field of view (1.96 mm2 at 10X)

  • Long working-distance objectives ranging from 2X to 40X

  • Transmitted light and Phase Contrast imaging for non-fluorescent samples

  • Multi-day, time-lapse imaging with temperature, humidity and CO2 control for live cells

  • Unattended screening of up to 45 fixed plates per run

  • Automated, fully customizable 2D and 3D image analysis on our MetaXpress workstations. Images can be exported for analysis in other packages

  • Sample prep facilitated by two MultiDrop384 dispensers and a BioTek plate washer

Zeiss AxioScan 7

Zeiss AxioScan 7 Whole Slide Scanner

Fluorescence and Brightfield modes

Features include: 

  • 100 slide capacity

  • Colibri 7 LED Fluorescence illumination source with excitations peaks at 385, 430, 475, 555, 591, 631, 735

  • Fluorescence detection for DAPI, CyanFP, GFP, YFP, Alexa 555, mcherry, CY5, CY7

  • 10x, 20x objectives

  • Zeiss Axiocam 705 color CMOS5 megapixel (for brightfield) and Axiocam 712 mono R2 (for Fluor)

  • Scan profiles to facilitate operation & reproducibility

  • Zeiss ZEN imaging software

Incucyte SX5 HD/3CLR Live-Cell Analysis System (Sartorius)

in-incubator microscope for extended time-lapse imaging

Incucyte SX5

Features include: 

  • HD/G/O/NIR triple filter cube and G/R double filter cube available

  • 4x, 10x and 20x objectives

  • Holds 6 Microplates (other vessels formats available)

  • Phase Object counting

  • Fluorescence Acquisition/Processing software module

  • Whole well imaging

  • Incucyte Cell-by-Cell software

  • Cell Migration Kit w/96-well woundmaker & Scratch/wound analysis

  • Chemotaxis software module

  • Spheroid Software module